Tag: 爱上海LL

Pertamina enlists Krakatau Steel as supplier for Rokan Block

first_imgPertagas president director Wiko Migantoro said the deal was a means of using more locally made components within the Rokan Block, which is Indonesia’s second-most productive oil block.“This is mainly an effort to create synergy among state-owned enterprises and their subsidiaries in key national projects,” he said in a joint statement, adding that the deal would cut pipe purchasing costs by 16 percent.Indonesia, through Pertamina, is set to nationalize the Rokan Block next year. The area is currently operated by United States-based Chevron.Read also: Pertamina loses partners, eyes new investors for refinery megaprojectsThe country expects Pertamina’s takeover to maintain block production levels, which saw a landmark decline of 9.2 percent year-on-year to 190,131 barrels per day in 2019. Prior to 2019, the Rokan Block was Indonesia’s most productive oil block.“We guarantee punctuality on the lead time of 4-6 months, so that this project can be finished on time and with quality,” said Krakatau Steel president director Silmy Karim.Topics : State-owned energy giant Pertamina has enlisted fellow state-owned company Krakatau Steel to supply metal sheet coils for the former’s project in the Rokan oil and gas block in Riau.Pertamina, through subsidiary Pertamina Gas (Pertagas), signed on Tuesday a deal with Krakatau Steel, the country’s largest steelmaker, to purchase 53,600 metric tons of hot rolled coil (HRC) steel, which will be turned into 370 kilometers of piping for the project.Read also: SOE Ministry slashes Pertamina’s board of directors to refocus businesslast_img read more

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K9 Axel finds drugs during traffic stop

first_imgNorth Vernon, IN—Thursday,  Sergeant Cody Low with the Jennings County Sheriffs Office and his canine partner, Axel, conducted a traffic stop on Country Squire Blvd involving a Silver 2004 Pontiac Sunfire for a registration violation. Sgt. Low made contact with the driver, Jason Jackson, 35, of North Vernon, who was found to be driving on a suspended license. Sgt. Low deployed his canine partner Axel to conduct a free air sniff of the vehicle. Canine Axel gave a positive alert to the odor of Narcotics coming from inside the vehicle. A search of the vehicle yielded over 3.5 grams of methamphetamine, four syringes, and paraphernalia. The passenger, Johnny Zolton,65, of North Vernon, was also taken into custody on drug charges.Johnny Zolton was charged with Possession of Methamphetamine and Possession of Paraphernalia.Jason Jackson was charged with Possession of Methamphetamine, Possession of Paraphernalia, Possession of Syringe, and Driving While Suspended Prior.last_img read more

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Lambert accepts criticism

first_imgLiverpool striker Rickie Lambert admits he cannot argue with criticism of their lack of physical and mental toughness. Press Association “We lost the individual battles and it wasn’t good enough,” said the £4million summer signing from Southampton, who is likely to start in Bulgaria in the absence of the injured Mario Balotelli having finally got off the mark for his new club against Palace. “There wasn’t anyone in a Liverpool shirt who was good enough and it was wholly down to the players on the pitch. “I do believe it is a lack of confidence at the minute but that will come back. “It is not going ideally but it is up to the players on the pitch to ‘dog’ the performances out. “Whatever the result in any game we have to perform better than we did at the weekend. “It is totally down to the players. They are desperate to get the game under way and try to rectify our performance at the weekend. “Win or lose we have to put in a performance of the standard of a Liverpool team.” Despite a four-match losing streak and poor performances all round, manager Brendan Rodgers retains the confidence of owners Fenway Sports Group and has had messages of support from them this week – although he has not spoken to anyone in person. He has urged his players to display some “aggression and tenacity” which has been lacking this season, starting against Ludogorets as they seek to keep their hopes of progress to the knockout phase of the Champions League alive. “It can happen. It is something that you work towards,” Rodgers said. “Sometimes it takes one moment that can change a season for you and that is something that we have to believe can happen. “It has happened as of late and apart from a half in a game, or the game at Tottenham, we haven’t been anywhere near our levels. “But one thing you can never do is give up. We keep working in the belief that the honesty and belief of the group will get us the results.” Liverpool have lost their last three Champions League games – they have never lost four in succession in the same season and never been defeated in all three away games in a European group stage. Goals have been a problem with the two they scored against Ludogorets back on September 16 their only efforts so far – and one of those was an added-time penalty winner from Steven Gerrard. In the wake of Sunday’s 3-1 defeat at Crystal Palace ex-Reds defender Jamie Carragher said the team was lacking in leaders and was bullied in games. Lambert accepts, on that occasion, the former vice-captain’s assessment was right, but he insists the players are determined to put things right against Ludogorets in the Champions League. last_img read more

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QA Should all animal experiments be listed in a public registry

first_img Email Daniel Strech, a bioethicist at Hannover Medical School in Germany. Animal research has a publication problem. About half of all animal experiments in academic labs, including those testing for cancer and heart drugs, are never published in scientific journals, and those that are have been notoriously hard to replicate. That’s part of the reason that most drugs that work in animals don’t work in people—only 11% of oncology compounds that show promise in mice are ever approved for humans—despite billions of dollars spent by pharmaceutical and biotech companies. Meanwhile, academic labs waste money, mice, and other resources on experiments that, unbeknownst to them, have already been done but were never reported.In response to similar concerns about human studies, the U.S Food and Drug Administration (FDA) in 2007 mandated that researchers conducting human clinical trials preregister the details in an online database like ClinicalTrials.gov. Now, some scientists are wondering whether a similar approach makes sense for animal experiments. In a study published this month in PLOS Biology, Daniel Strech, a bioethicist at Hannover Medical School in Germany, and colleagues investigated the idea of so-called animal study registries. They scoured the literature and interviewed nearly two dozen scientists to determine the pros and cons of such registries—and whether they would actually make a difference. Strech chatted with Science to discuss the group’s findings. This interview has been edited for clarity and length.Q: What would these registries look like? Karin Kaiser/Hannover Medical School Click to view the privacy policy. 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Country A: Before they start their animal experiments, scientists would need to document the details of the proposed study in an online database. This would include information like sample size, planned duration of study, how the experiments will be controlled, and the planned statistical analysis. A lot of these details are missing in scientific publications, which allows researchers to change their methodology after they begin a study to get the outcome they want.Q: What are the advantages of such registries?A: Animal researchers are supposed to avoid unnecessary and duplicative studies. If they are thinking about conducting a study, but a registry reveals that a similar study has already been done or is in progress, they might not do it. Or they may contact the team to try to set up a collaboration. The data could also help them refine their own study; if they’re trying to figure out what dosages of an antibiotic are most effective, for example, they can avoid dosages that another group has already tested.Transparency is also a big advantage. Researchers might be less likely to register a poorly designed animal study if they know other scientists will see it, and that might stop them from conducting the study. And if you register a study with 20 mice but then only publish results with 13 mice, people are going to wonder what happened to the other seven mice. That could cut down on publication bias. Q: What are the disadvantages? A: One of the biggest differences between human registries and animal registries is the use of experimental therapies or compounds in animal studies that aren’t known to the wider scientific community. So a lot of people are concerned about the theft of ideas—that another, bigger lab could take your idea and do it quicker. Animal registries could get around this concern by instituting a confidentiality timeframe, where others couldn’t access your registry until after you publish your work. You could also limit the level of detail you give.Some say animal registries would also add unnecessary regulations and paperwork. But to me it seems much less time intensive than all of the other things you have to do for this research—getting funding, approval, etc. Researchers are increasingly using digital versions of their protocol; you could just submit that.Finally, some researchers worry that even though these registries are supposed to reduce the number of animals in biomedical research, their labs may end up using more animals because they feel they need larger sample sizes to conduct more robust research as part of these registries. Others say we’ll use fewer animals because overall the studies will be less wasteful. Either way, a lot of researchers are concerned that animal registries will tip off animal rights activists. I was surprised how often that concern came up. But nowadays you don’t need a registry to know which university is doing which research with animals. Q: Will animal registries really have an impact?A: Registries don’t directly decrease publication bias; they just shed more light on it. But they do provide a lot of incentive for researchers to eventually publish something. And registries should reduce redundancy regardless. In our study, people told us that, of course, they would check a registry to make sure a study hasn’t already been done.With human registries, it’s been less than a decade since the FDA said all human clinical trials had to be registered. So it’s hard to tell how effective these registries have been. We also don’t know what the real publication bias was in human trials, so it’s hard to compare what has changed.Q: Are you advocating for these registries?A: When we started looking into this, we just wanted information. Now, I think the case is very clear that we need something like these registries. We need to design them as best as possible to address the interests of researchers, funders, and animals. But I’m still not clear what they should look like.Q: What’s next?A: If we want these registries to become a reality, we need a government agency like the FDA to mandate them. Journals could also require that a trial be registered as a condition for publication. Universities could advocate that their labs participate as well. In the meantime, groups like ours are working on a survey to determine how important the perceived strengths and weaknesses of these registries are to different stakeholders. It took decades from the first ideas of having a registry for human clinical trials to the reality in 2007, but I don’t think it will take that long for animal registries. I think we can skip some of those debates now, because we have solved some of the problems.last_img read more

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