FORT ST. JOHN, B.C. – The City of Fort St. John is inviting residents to ask questions and give feedback during a public meeting next Monday when the City’s 2017 Annual Report will be released.The 75-page document highlights the City’s accomplishments and whether goals were met in 2017 as well as its goals for this year. The report also includes the City’s 2017 audited financial statements and a report on permissive property taxes.Copies of the report are available via this link: http://www.fortstjohn.ca/node/27966, or can be picked up at City Hall. The Council Chambers at City Hall will be the venue for the public meeting, which is taking place at 6:00 p.m. on Monday, June 25th.
Ohio State redshirt-junior Logan Stieber takes down Notre Dame College sophomore Maurice Miller in the 141-pound match Nov. 15 at St. John Arena. OSU won, 29-11.Credit: Ethan Day / Lantern photographerFor the third straight year, Logan Stieber is the nation’s best.The Ohio State redshirt-junior wrestler became the first Buckeye in program history to win three national titles after defeating No. 4-seed Virginia Tech redshirt-junior Devin Carter Saturday in the 141-pound weight class in Oklahoma City.“(This) feels great,” Stieber said after the victory, according to an OSU press release. “I know Devin is a really, really tough individual … It felt good to get through my offense and ride hard. And my defense was great and I just kept getting after him.”Stieber, a three-time All-American and three-time Big Ten Champion, earned the crown in what was his 21st consecutive match win after jumping out to a 2-0 lead by the end of the first period. Entering the third period with a 5-0 advantage, a pair of takedowns helped him secure the 10-1 win.Stieber wasn’t the only Buckeye wrestler to compete for a national title, as senior Nick Heflin fell in the 197-pound weight class final to Missouri freshman J’Den Cox, 2-1.Heflin, also a three-time All-American and 2014 Big Ten Champion, narrowly missed out on the title as he almost scored a takedown when time expired. That would have given him a 3-2 victory, but after an official review, the call was confirmed.In the team competition, OSU finished sixth after totaling 57 points. Penn State won its fourth straight national championship after finishing with 109.5 points as a team.
On February 22, Vale celebrated the laying of the first track of the Conakry-Kankan railroad, marking the start of the reconstruction of the main link between Conakry and Kankan in Guinea. In April 2010, Vale announced it would invest in Guinea’s Simandou, which will be the largest integrated iron ore mine and infrastructure project ever developed in Africa. Simandou’s first phase involves the development of the Zogota mine, with a dry processing plant, a dedicated railroad and a maritime terminal in the coast of Liberia, as well as a 100km rail spur connecting this railway to Zogota, in Guinea. The initial phase is scheduled to start production in 2012 and will have a capacity of 15 Mt/y. The project’s second phase involves capacity reaching 50 Mt/y in 2020, stemming from the development of blocks 1 and 2, and an additional rail spur connecting them to Zogota.The reconstruction of the Conakry-Kankan is part of Vale’s commitment to the development of Simandou and Guinea’s economic growth. As part of an agreement with the government of Guinea, Vale is investing to refurbish the railroad, used for passenger and general cargo transportation between Guinea’s Conakry capital city and Kankan in the eastern part of the country. With the railway’s rehabilitation, Vale aims to contribute to the social and economic development of the West African nation, potentially creating several thousands of jobs. With Simandou, Vale hopes to bring significant social and economic benefits to the Guinean population. The Conakry-Kankan line, run by the Office National des Chemins de Fer de Guinée, has not operated since 1983. The government’s goal is to rehabilitate the line in cooperation with Vale. The railway was initially built between 1900 and 1914 and had 45 stations. It plays an essential role by serving several towns and opening up the entire sub-region.
Rat à trompe géant : une nouvelle espèce identifiée ?Kenya – Les naturalistes de la société zoologique de Londres ont obtenu, grâce à des pièges photographiques disposés dans une forêt reculée du Kenya, des images de ce qui pourrait être un nouveau-venu dans la famille méconnue des rats à trompe. C’est après avoir repéré ce qui lui a semblé être un rat à trompe inconnu que Grace Wambui a décidé de “piéger” le mystérieux animal grâce à des appareils photo à déclenchement automatique. Pari gagné pour cette naturaliste, membre d’une équipe de la société zoologique de Londres (ZSL) qui explore la biodiversité de la forêt de Boni-Dodori, dans le nord-est kenyan.À lire aussiLe remarquable sauvetage d’un petit éléphant orphelin au KenyaD’après les biologistes de la ZSL, le petit mammifère au long museau flexible en forme de trompe pourrait bien être une nouvelle espèce de Macroscelidea, ou rat à trompe. Ce groupe zoologique compte à ce jour dix-sept espèces qui, malgré leur nom, ne sont pas des rongeurs.Enthousiasmés par cette découverte, les biologistes de l’équipe devront cependant poursuivre leurs études pour déterminer s’il s’agit bien d’une nouvelle espèce. Voilà qui, en tout cas, les conforte dans leur conviction que ces forêts, mal connues à cause de leur accès difficile et de l’insécurité qui règne dans la région, sont dotées d’une riche biodiversité. Selon Sam Andanje, du département de la vie sauvage du Kenya, des mesures de préservation s’imposent pour cette zone côtière, menacée par un développement rapide. Le 17 septembre 2010 à 15:32 • Emmanuel Perrin
Patrick Timm is a local weather specialist. His column appears Tuesdays, Thursdays and Sundays. Reach him at http://patricktimm.com. The almost full moonrise Sunday evening was nothing less than spectacular. And I know the actual full moonrise Monday evening was probably also outstanding. It is so nice to have some nice clear skies and an autumn feel to the air. Could you feel it Monday?I certainly could feel fall in the air with the brisk dry northerly wind. With the dry and cool air mass many locations here in Clark County dipped into the 30s, with at least a few readings at the frost point. East of the Cascades in Washington and Oregon, overnight lows plummeted into the low to mid-20s. It is that time of the year, I guess.We will see highs at 80 degrees or higher today through Friday as a large area of warm high pressure holds strong. Some computer models show increasing clouds and a chance of rain or showers this weekend but I think as the week wears on that may change and we will continue to have dry weather on Saturday and Sunday. Stay tuned.Meanwhile, Monday around the Evergreen State, afternoon temperatures were in the low to mid-60s north of Chehalis and in the low 70s south to Vancouver. The overnight lows will continue to be on the cool side, so a jacket is appropriate for the early morning school bus. Good luck trying to get the kids to wear an outer garment.Vancouver dipped to 43 degrees Monday for the low, with the average low now at 49 degrees. The afternoon high temperature as of 5 p.m. was 72 degrees, one degree below average for the date.
More than a few magazine and media executives spent the holidays putting the finishing touches on deal closures. We’re only 3 weeks into January and there’s been a flurry of M&A action—from decently big deals to small. Here’s a recap:Today of course Meredith announced it’s buying Allrecipes.com from Reader’s Digest Association, advancing a deep dive strategy into the food vertical as fast as RDA is pulling away from it, having also bought Everyday With Rachael Ray from them. The deal closely followed Meredith’s acquisition of FamilyFun from Disney Publishing earlier in the month. Harry Stagnito has sold Stagnito Media to private equity firm Topspin LBO, which also owns his son’s Vermont-based Moose River Media. The deal, says Stagnito, will allow the company to build out its marketing services and data and information products. Edwin V. Avent’s Heart & Soul magazine has been sold to a group of investors called Brown Curry Detry Taylor & Associates. BCDT’s principals all have direct ties to the magazine, having worked for it in one capacity or another.Hanley Wood is now owned by Oaktree Capital Management, Strategic Value Partners and Tennenbaum Capital Partners after going through a major recapitalization, cutting its debt from $410 million to $80 million.In a retreat from the U.S. market, Future plc sold its U.S. group’s Music Division, including 3 magazines, to NewBay Media for $3 million. Revenues for the group in Future’s fiscal 2011 were about $13 million. Grand View Media has taken over management of Shooting Sports Retailer magazine. While not technically a sale, Grand View may have an option to buy after a certain period of time and certain performance goals are met.F+W Media is expanding its food vertical coverage, too. It bought World Tea Media, which produces the World Tea Expo as well as associated editorial products. Vibe Holdings has been merged with BlackBook Media and Access Network, forming Vibe Media. The combined entity will be owned by the Yucaipa Johnson Fund, backed by Ron Burkle and Earvin “Magic” Johnson, and InterMedia Partners.Bangor Metro, a regional magazine serving the Bangor, Maine region, has been sold to Cashman Asset Management.
10 varieties of cookies arranged in the Governor’s Mansion dining room for the annual open house on December 11, 2018 (Photo by David Purdy/KTOO)On Tuesday afternoon, Gov. Mike Dunleavy hosted the annual holiday open house at the governor’s mansion in Juneau. The event was an opportunity for the community to meet the governor and first lady in their new home, as well as sample a few cookies.That second part is a big priority for some of the open house’s younger guests.“We go pretty much every year,” said 11-year-old Dane Hubert, waiting in line on Calhoun Avenue with his younger brother Jaeger and their parents. Asked his favorite kind of cookie, Dane replied, “That’s a hard decision. … There’s a lot of different types of cookies.”“The M&M one is really good,” Jaeger supplied.Juneauites — mostly families like the Huberts — lined up outside in the snow starting around 3 p.m. Volunteers ushered guests into the elaborately decorated mansion to shake hands with Dunleavy, Lt. Gov. Kevin Meyer and their wives, and then on to the dining room where cookies were already piled high. Children’s music groups performed in the living room as guests milled around, admiring gingerbread houses and sipping cider.This year all 10 varieties of cookies were baked in-house by mansion staff and Creations by Cynthia. Lisa Boman, executive residence manager, said that cookie dough preparation for the holiday meet-and-greet started in late September and wrapped up by the end of October.“We have a little over 23,000 cookies out there,” she said. “And in order to do that in-house, two people, it was a project.”In her seven years as residence manager, Boman says they’ve never run out of cookies. Leftovers go to nonprofits in Juneau like the AWARE shelter, the fire and police departments and the Glory Hall.Gov. Dunleavy’s favorite cookie, if you were wondering?“Chocolate chip,” he said. “More chocolate than chip — I guess, more chocolate chip than dough.”
New Delhi: Prime Minister Narendra Modi is all set to hold bilateral talks with French President Emmanuel Macron during his two-day state visit to France from August 22 with an aim to strengthen cooperation in the fields of defence, maritime security, counter-terrorism, and civil nuclear energy along with robust trade and investment relations. The prime minister will arrive in France on Thursday evening and will straightaway head to talks with Macron, who will also host a special dinner for Modi at the Chateau de Chantilly, a 19th-century site located in Oise, 60 km from Paris. Also Read – BJP launches anti-AAP campaign to save Delhi Advertise With Us During his visit to France, the prime minister is also scheduled to address the Indian community in Paris and also inaugurate the Memorial for the Indian victims of the Air India crashes at Nid D’Aigle. “The bilateral visit to France and the invitation to G7 Summit are in keeping with the tradition of strong and close partnership and high-level political contacts between India and France,” the Ministry of External Affairs said in a statement. Also Read – In his first after abrogation of Art 370, Army chief to visit Srinagar today Advertise With Us Informed sources have told ANI that significant talks on climate change, financing, and collaboration for green technologies, specific roadmap and open partnership in new areas like digital and cyberspace, and skill development will be the key thrust of the visit and agreements in this regard will be inked. Agreements on collaboration in science and technology are also expected. However, no agreement on defence cooperation is on the cards. Discussion on future roadmap vis-a-vis defence collaboration is expected, sources said. Advertise With Us The issue of Jaitapur nuclear reactors may also come up during the prime minister’s visit. Informed sources said the talks on the cost-effectiveness of reactors are moving in the right direction and there is no roadblock. There will also be discussions on regional issues like Iran, the peace process in Afghanistan and terror financing, they said. Interestingly, Modi is visiting France ahead of the Financial Action Task Force (FATF) meet in Paris. The Paris-based anti-money laundering watchdog, also known by its French name — Groupe d’action financiere — is an intergovernmental organisation founded in 1989 on the initiative of the G-7 to develop policies to combat money laundering. In 2001, its mandate expanded to include terrorism financing Informed sources say that any action on Pakistan on terror financing will be considered only after seeing the report submitted by Pakistan. When asked whether India-Pakistan tension post abrogation of Article 370 will come up in during Modi’s visit to France, informed sources told ANI that French position is clear that it is a bilateral issue. Speaking about recently concluded UNSC meet on Kashmir where France reportedly favoured Indian position, informed sources said: “France is not just a partner of India but it is a friend in need.” A very comprehensive and significant joint statement will also be issued. Indian and French leadership will also exchange notes on their respective positions on G-7. From France, the prime minister will leave for a bilateral visit to UAE and Bahrain and will return to Biarritz city in France to attend the G7 summit wherein he will focus on how India has been approaching issues of climate change and biodiversity, and also showcase how it has used technology to boost inclusive development. On the sidelines, the prime minister will be having bilateral meetings with leaders of other countries. Modi will on Friday arrive in the UAE he where will receive the Order of Zayed, the UAE’s highest civilian honour that was conferred on him in April for boosting bilateral ties. Meanwhile, his visit to Bahrain will mark the first by any Indian prime minister to the country. Modi will meet Bahrain Prime Minister Prince Khalifa bin Salman Ali Khalifa and discuss bilateral and international issues.
Everything old is new again—but with a modern twist.From vinyl records to typewriters, vintage tech is making a comeback, and Lomography is climbing aboard with the new Simple Use Film Camera.A long-time proponent of analogue and digital photography, Lomography has introduced a 21st-century disposable shooter.AdChoices广告The pocket-sized Simple Use cam comes in three models, each loaded with a different “funky” 35mm film: Produce classic analogue images with Color Negative ISO 400, make moody monochrome magic with Lady Grey ISO 400, or tint your world purple with LomoChrome Purple ISO 400.For $16.90 each, the Color Negative and LomoChrome Purple also feature three color gel clash filters; mix and match yellow, magenta, and cyan gels to create six different hues. The black-and-white version costs $21.90; bundle all three cameras for $52.92.via LomographyBefore snapping any pictures, get into the right state of mind by jamming to Hootie & the Blowfish, feeding your Tamagotchi, and guzzling a Zima.Photographers of a certain age will no doubt remember the intricacies of using a disposable camera: Turn the film advance wheel, stand no more than seven feet from the subject, press the shutter release button, turn the film advance wheel.And, for the love of all that is holy, remember to activate the flash—hold down flash button until the indicator turns red—when shooting anywhere that isn’t a well-lit room or sunny landscape.When the film counter turns to “E,” open the back door, remove the roll, and mail it back to 1994 get it developed at any lab.Intended for single use only, the Simple Use Film Camera can be restocked, at your peril (opening it is not covered by any warranty or guarantee).Boasting a 31mm lens focal length, 1/120s shutter speed, and f/9 aperture, the handheld camera requires one AA battery and 15-second flash recharge time after each snapshot. Photos: Animals Rescued From Illegal Trafficking in ColombiaEagle Steals Rabbit From Fox in Mid-Air Battle Stay on target
(Phys.org) —The ability of a cell to move, replicate, and recast itself according to the needs of the organism which it serves, comes at it price. The extreme flexibility of cells takes its origin from the constant turnover of nearly every component with which they are made. There are a few exceptions to this general principle for a few protected regions like, for example, the lens of the eye, or the collagen matrix within the extracellular space. In a new paper published in Cell, researchers show that certain components of the pore complex that controls the flow of components out of the nucleus, escape the normal turnover cycle, and may persist for the lifetime of the cell. Some Nuclear pore complex proteins can last for the lifetime of the cell. Credit: learn.genetics.utah.edu More information: Identification of Long-Lived Proteins Reveals Exceptional Stability of Essential Cellular Structures, Cell, Volume 154, Issue 5, 971-982, 29 August 2013. DOI: 10.1016/j.cell.2013.07.037AbstractIntracellular proteins with long lifespans have recently been linked to age-dependent defects, ranging from decreased fertility to the functional decline of neurons. Why long-lived proteins exist in metabolically active cellular environments and how they are maintained over time remains poorly understood. Here, we provide a system-wide identification of proteins with exceptional lifespans in the rat brain. These proteins are inefficiently replenished despite being translated robustly throughout adulthood. Using nucleoporins as a paradigm for long-term protein persistence, we found that nuclear pore complexes (NPCs) are maintained over a cell’s life through slow but finite exchange of even its most stable subcomplexes. This maintenance is limited, however, as some nucleoporin levels decrease during aging, providing a rationale for the previously observed age-dependent deterioration of NPC function. Our identification of a long-lived proteome reveals cellular components that are at increased risk for damage accumulation, linking long-term protein persistence to the cellular aging process. The ‘weakest link’ in the aging proteome Journal information: Cell Extracellular proteins, like crystallins of the lens, or components of cartilage, accumulate damage over time that compromises their function. Clouded vision or stiff joints are the familiar result. Inside cells however, an intricate accounting system exists whereby proteins are stochastically festooned with sequential markers for degradation—much like a trainee might predictably progresses through the colored ranks of Karate. In yeast, it has been reported that the average protein half-life is just 90 minutes, while for mammals it may be more like 1 or 2 days.An exception to this rule is our DNA, which owes its long life to dedicated repair mechanisms that patch up damage. For proteins however, no such sequence-level mechanisms are known to exist. The histone proteins that bind DNA have also been observed, in some cases, to be exceptionally long-lived. Measuring these lifetimes reliably, particularly for the older generation, requires some special experimental considerations. The researchers used a method called pulse-chase labeling, which requires feeding newborn rats a diet containing exclusively the 15N isotope as the pulse. A normal 14N diet, the chase, was begun after 6 weeks, and the animals then sacrificied at various times over the ensuing year. The cellular components were then fractionated and mass spectrometry was used to comprehensively identify long-lived proteins in the brain. The lifespans of a few components of the nuclear pore complex (NPC) were particularly striking. The NPC contains multiple copies of over 30 different subvarieties of the nucleoporin (Nup) family alone. Two particular subcomplexes of Nup proteins, which serve as scaffold components, where found to resist degradation. The researchers also measured translation levels of these and 11,000 other proteins to measure synthesis levels concomitantly. Every long-lived protein was found to also be actively involved in translation.Unlike other large protein complexes, such as ribosomes or proteasomes, the NPC apparently does not turnover as an entire complex. Instead individual subcomplexes are exchanged at specific rates as new copies are synthesized. What mechanisms might administer this exchange, if any, are as yet unknown. The researchers found, in particular, that 25% of those proteins within a certain complex (Nup205), have not been replaced after a year. Together with the histone H3.1 protein, that stat earns them the title of most persistent mammalian intracellular protein. The authors speculate that disassembly of entire NPCs might not be practical for the cell because dismantling these key components could jeopardize the integrity of the nuclear envelope. Important nuclear substructure, possibly including epigenetic depots critical for transmitting information beyond the lifetime of an individual cell might then be compromised. They also note that long-lived proteins might also be sources of vulnerability within the proteome, particular those that would be exposed to harmful metabolites or chemical interlopers. Identification of these elements may therefore be important in understanding the aging process in postmitotic cells. Citation: Protein lifetime and the stability of cell structures (2013, September 4) retrieved 18 August 2019 from https://phys.org/news/2013-09-protein-lifetime-stability-cell.html Explore further © 2013 Phys.org This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
“Michael, we’re not gonna fight about this okay?” “Paul, I think I told you, I’m a lover, not a fighter.”“She told me that I’m her forever lover,” said Paul “You know, don’t you remember?”“Well, after loving me,“ Michael answered, “she said she couldn’t love another.”“Is that what she said?”“Yes, she said it, you keep dreaming.”This playful exchange happened between former Beatle Paul McCartney and Michael Jackson during the 1982 hit music video “The Girl is Mine.” The video featured a make-believe rivalry between the two pop stars over the affections of a young lady.Paul McCartney. Photo by Oli Gill CC BY-SA 2.0Three years later, McCartney and Jackson would lock horns in a real-world battle, but not over a girl.According to Billboard Magazine, the conflict started in 1985, when Jackson paid nearly $50 million to ATV Music (now called “Sony Music”) to purchase a 4,000-song catalog.Michael Jackson performing his song “Jam” as part of his Dangerous world tour in Europe in 1992. Photo by Casta03 CC BY-SA 3.0The catalog contained 250 songs by the John Lennon/Paul McCartney songwriting duo. It also included tracks by Elvis Presley, the Rolling Stones, and Bruce Springsteen.Paul McCartney was not happy about having his own songs purchased out from under him by another artist. To add more insult to injury, Jackson had actually outbid McCartney on the deal.John Lennon (left) and Paul McCartney (right) in 1964.The fact that McCartney and Jackson were friends and had recorded multiple songs together – including: “Say, Say, Say,” “The Girl is Mine,” “The Man” and “Girlfriend,” – surely made the deal more of a betrayal. Their friendship never recovered.But how did Paul McCartney, one of the most famous pop songwriters of the 20th century, end up in a position where another artist could buy the rights to his songs?When The Beatles’ debut album “Please Please Me” was released in March 1963 their manager, Brian Epstein, published the songs with the company Northern Songs.Please Please Me, side 1, with original Parlophone gold and black label. Photo by Parlophone Records CC BY-SA 3.0The company was primarily owned by Epstein himself and by publisher Dick James, along with John Lennon and Paul McCartney. George Harrison and Ringo Starr – the other two Beatles songwriters – split ownership of the remaining 40 percent.Northern Songs became a public company in 1965, with Lennon and McCartney owning 15 percent each and with Harrison and Starr sharing a small percentage. Harrison was not happy about this, and even wrote a song about his meager cut in the deal.Jackson performing in June 1988. Photo by Zoran Veselinovic CC-BY-SAIn 1969, Dick James sold his stake in the company to ATV Music. John Lennon and Paul McCartney tried to outbid ATV, but they didn’t have enough money. After ATV had taken control of the Beatles’ song catalog, Lennon and McCartney sold their company stakes to ATV as well.So, when ATV Music went up for sale, they offered McCartney one more chance to bid on the rights to the Lennon-McCartney song catalog. This is when Michael Jackson stepped in and paid $47.5 million to become the owner of the catalog.McCartney and Lennon, 1964.In 2006, the matter became more complicated for McCartney when Michael Jackson, faced with a potential bankruptcy, agreed to sell half of his ownership in the company back to Sony/ATV. This would give Sony 75 percent ownership of the Lennon-McCartney song catalog, which, according to The New York Times, was then worth about $1 billion.McCartney was left with only one shot to get his songs back. According to the United States Copyright Act of 1967, any publishing rights to songs written before 1978 could be regained by their author after 56 years. Since the first Beatles songs had been written between the years of 1962 and 1963, McCartney would have to wait until 2018 before he could hope to get his songs back.Michael Jackson’s star on the Hollywood Walk of Fame.Then, in 2009, Michael Jackson died by overdosing on the anesthetic “propfol” – he was 50 at the time. Jackson’s share of the Lennon-McCartney catalog became a part of his estate, which was controlled by his attorney John Branca and by John McClain.In 2015, McCartney began the fight to reclaim 32 Beatles songs written in 1962. In 2016 Sony finally agreed to pay $750 million to buy out the half of Sony/ATV which was owned by the Jackson Estate. This made Sony the sole owner of 750,000 songs, including the Lennon-McCartney catalog.Read another story from us: A Hard Day’s Night (in Jail): Paul McCartney Arrested for Arson in 1960This deal marked the official end of Jackson and McCartney’s battle – which had literally become a fight to the death. According to Billboard Magazine, Sir Paul McCartney finally regained the Beatles’ song catalog in June of 2017, just a few days before his 75th birthday.
Speaking to West Australia, Court claimed that she lost the re-election in a “politically motivated” vote which “silenced” her.Talking about being dumped by the club, Court described it as “sad”.She said: “You don’t have the freedom of speech today to really defend yourself.“It’s a sad day for our nation when it comes to that”.Ian Hutton, the president of the club, said that it was not only Court’s backwards views on marriage equality that led to the final vote but also her inability to attend club events.Related: Sigur Rós are trolling homophobic tennis player Margaret Court in the best wayChief executive of the club, Michael Roberts, said that Court’s views were “polarising” and so the outcome of the vote was inevitable.He said: “If you’ve got an opinion that’s very polarising, when you’re so firmly supportive or against something, then it’s going to have an impact on how you’re perceived in the community.“Obviously, her opinions had played a part in it, there’s no doubt about that.“Cottesloe Tennis Club, whether they meant to or not, have made a bit of a social stand by making the decision.”Share this:TwitterFacebookLike this:Like Loading… The string of abusive comments started earlier this year when she made a splash by likening gay people to Hitler.Court claimed that homosexuality is an ungodly “lust for the flesh”, that LGBT tendencies in young people were “all the devil”, and that older lesbian tennis stars have ‘converted’ younger players in a rant on a radio interview.More recently, she said that Christmas, Easter and Mother’s Day will be cancelled if the country votes in favour of equal marriage.Related: Gay couple ‘tie the knot’ in protest wedding outside of the Margaret Court ArenaCourt has now been voted out of the Cottesloe Tennis Club in Perth where she stood as the vice-patron for years. eTN Chatroom for Readers (join us) A famous homophobic tennis legend has been dumped as vice-patron of her club over her anti-same-sex marriage views.Margaret Court has become notorious for her homophobic rhetoric in recent months as the debate on same-sex marriage heated up. Tennis legend insists sexual abuse makes you gay, claims transgender children are SatanicAnti-gay voices are silenced according to tennis star Margaret CourtTennis player hints at boycott of Margaret Court ArenaPINK NEWS-
News | Mammography | August 14, 2019 Imago Systems Announces Collaboration With Mayo Clinic for Breast Imaging Image visualization company Imago Systems announced it has signed a know-how license with Mayo Clinic. The multi-year… read more Most women who undergo partial mastectomy (lumpectomy) surgery for breast cancer also complete a course of radiotherapy delivered to the whole of the affected breast (called external beam radiotherapy, EBRT). EBRT has been shown to reduce the risk of cancer recurring in the breast, but it can cause unpleasant side-effects, and requires women to attend radiotherapy centres for 20 days after surgery, which can cause serious difficulties for women who live far from radiotherapy centres, especially those in remote or very rural areas. In some cases, women who are eligible for lumpectomy may end up undergoing full mastectomy, simply because they cannot meet the demands of subsequent radiotherapy treatment required by partial tissue removal.Without radiotherapy treatment, women who undergo lumpectomy are at risk of the cancer recurring, usually either at, or near, the site of the original tumour. This has led several groups of researchers to investigate whether a single dose of radiation, specifically targeted to the site of the tumour, and delivered during or soon after surgery, might offer a viable alternative treatment to reduce the risk of recurrence. Two articles published today in The Lancet and The Lancet Oncologyreveal new results from two trials assessing two different methods of delivering targeted radiation in this way.TARGIT-A trialIn The Lancet, an international team of researchers, led by Professor Michael Baum and Professor Jayant Vaidya, of University College London, UK, investigated the performance of TARGIT (where radiation is delivered to the tumour site via a miniature X-ray emitting device) compared with a standard EBRT course of daily doses for 3 to 6 weeks. Over 12 years, 1721 women received the study treatment (TARGIT), compared to a control group of 1730 women who received standard EBRT treatment. The TARGIT technique was originally developed by Professor Michael Baum, Professor Jayant Vaidya, and Professor Jeffrey Tobias, and has been tested in 33 different centres since 1998.The 3451 patients who participated in the final analysis were made up from two separate strata, equivalent to two trials run in parallel. The first included 2298 patients, 1140 of whom received TARGIT at the same time of the initial surgery (as originally envisaged by the researchers); these participants were compared with 1158 patients receiving conventional EBRT. However, after receiving requests from some clinicians, they extended the trial to include 1143 women, 562 of whom were allocated EBRT, and 581 of whom were allocated to receive TARGIT as a second procedure an average of 37 days after surgery (postpathology stratum).The trial was intended to reflect real-life practice as far as possible, so women who had received TARGIT at the time of surgery but were subsequently shown to carry high risk features for recurrence also received EBRT. Overall, about 80% patients in the TARGIT group completed their surgery and radiotherapy under a single anaesthetic, without needing any supplemental EBRT.The researchers specified at the outset that if the difference in 5-year local recurrence between the two treatments was less than 2.5% then TARGIT should be considered “non-inferior” (as good as) standard radiotherapy. Across all trial participants, the difference in 5-year risk for cancer coming back in the breast (local recurrence) was within the originally set limit of 2.5%, meaning that a single TARGIT treatment was non-inferior to EBRT in controlling cancer. Furthermore, the overall mortality was 3.9% with TARGIT and 5.3% with EBRT, due to significantly fewer deaths from cardiovascular causes and other cancers. When TARGIT was given at the same time as lumpectomy, as the researchers originally planned, the local recurrence and breast cancer deaths were similar in the TARGIT and EBRT groups, and deaths from other causes were significantly reduced with TARGIT (1.3% for TARGIT vs. 4.4% for EBRT).According to Professor Vaidya, “The most important benefit of TARGIT for a woman with breast cancer is that it allows her to complete her entire local treatment at the time of her operation, with lower toxicity to the breast, the heart and other organs Our research supports the use of TARGIT concurrent with lumpectomy, provided patients are selected carefully, and should allow patients and their clinicians to make a more informed choice about individualising their treatment, saving time, money, breasts, and lives.”*ELIOT trialIn The Lancet Oncology, researchers in Italy, led by Professor Umberto Veronesi, of the European Institute of Oncology in Milan, report results from a trial of a slightly different method of delivering targeted radiation, using a device which emits electron radiation to the tumour site (electron intraoperative radiotherapy, or ELIOT). 651 women attending the European Institute of Oncology in Milan for early breast cancer treatment received ELIOT during lumpectomy surgery, and a control group of 654 women received standard EBRT after lumpectomy.The researchers distinguished between true local recurrence of breast cancer (occurring in exactly the same site as the tumour), and recurrence of cancer in the same breast that had been operated on (ipsilateral recurrence). In both cases, after 5 years, recurrence was significantly higher in the ELIOT group than the control group – 21 women (2.5%) in the ELIOT group experienced local recurrence, rising to 35 women (4.4%) when any ipsilateral recurrence was included, compared to just four women (0.4%) in the control group who experienced any recurrence.Despite the different rates of breast cancer recurrence, overall survival at 5 years did not differ significantly between the ELIOT and control groups (34 deaths in ELIOT vs. 31 deaths in the control group); there were no significant differences between the number of deaths due to breast cancer, or due to any other cause.For the patients in the ELIOT group, the researchers examined the characteristics of tumours where relapse occurred, allowing them to identify several features associated with recurrence, including large tumour (>2cm), and oestrogen-receptor negative (ER-negative).According to Professor Veronesi, “For women who receive intra-operative radiotherapy, identifying the features most commonly associated with recurrence of cancer in the breast that has been operated on will allow us to identify the patients most likely to benefit from subsequent external radiotherapy.””Although our results show that 5-year rates of local recurrence were significantly higher in women who received ELIOT, we need to bear in mind that for some women, the benefits of not needing to complete weeks of radiotherapy will outweigh a higher risk of local recurrence. It’s also encouraging that after 5 years, overall mortality rates do not differ between women who received ELIOT and those who received standard treatment. Advances such as intraoperative radiotherapy might help to further improve the quality of life for patients, and the findings of our trial will enable clinicians to better use biomolecular factors along with traditional clinical and histopathological factors to identify the patients who are ideal candidates for partial breast irradiation.”Writing in a linked Comment on both studies, Professor David Azria and Dr Claire Lemanski of the Institut du Cancer Montpellier, France, suggest that although it is clear that further research will be needed to identify the patients least likely to experience recurrence of cancer after undergoing surgery and intraoperative radiotherapy, “The new data from TARGIT-A and ELIOT reinforce our conviction that intraoperative radiotherapy during breast-conserving surgery is a reliable alternative to conventional postoperative fractionated irradiation, but only in a carefully selected population at low risk of local recurrence.” News | PACS | August 09, 2019 Lake Medical Imaging Selects Infinitt for Multi-site RIS/PACS Infinitt North America will be implementing Infinitt RIS (radiology information system)/PACS (picture archiving and… read more Following radiation, the bone marrow shows nearly complete loss of blood cells in mice (left). Mice treated with the PTP-sigma inhibitor displayed rapid recovery of blood cells (purple, right). Credit: UCLA Broad Stem Cell Research Center/Nature Communications News | Brachytherapy Systems | August 14, 2019 Efficacy of Isoray’s Cesium Blu Showcased in Recent Studies August 14, 2019 — Isoray announced a trio of studies recently reported at scientific meetings and published in medica read more News | Neuro Imaging | August 16, 2019 ADHD Medication May Affect Brain Development in Children A drug used to treat attention-deficit/hyperactivity disorder (ADHD) appears to affect development of the brain’s… read more News | Pediatric Imaging | August 14, 2019 Ultrasound Guidance Improves First-attempt Success in IV Access in Children August 14, 2019 – Children’s veins read more News | Artificial Intelligence | August 13, 2019 Artificial Intelligence Could Yield More Accurate Breast Cancer Diagnoses University of California Los Angeles (UCLA) researchers have developed an artificial intelligence (AI) system that… read more Catalyst PT image courtesy of C-RAD News | Radiation Therapy | August 16, 2019 Drug Accelerates Blood System’s Recovery After Radiation, Chemotherapy A drug developed by UCLA physician-scientists and chemists speeds up the regeneration of mouse and human blood stem… read more Image courtesy of Imago Systems The MD Anderson Proton Therapy Center expansion is expected to be completed in 2023. Rendering courtesy of Stantec. Related Content Feature | December 16, 2013 One-stop Radiotherapy May Offer Alternative to Lengthy Post-surgery Procedures for Breast Cancer New study shows that intraoperative radiotherapy during breast-conserving surgery is a reliable alternative to conventional postoperative fractionated irradiation FacebookTwitterLinkedInPrint分享 Images of regions of interest (colored lines) in the white matter skeleton representation. Data from left and right anterior thalamic radiation (ATR) were averaged. Image courtesy of C. Bouziane et al. News | Patient Positioning Radiation Therapy | August 15, 2019 Mevion and C-RAD Release Integration for Improved Proton Therapy Treatment Quality Mevion Medical Systems and C-RAD announced the integration between the C-RAD Catalyst PT and the Mevion S250i proton… read more News | Radiation Therapy | August 15, 2019 First Patient Enrolled in World’s Largest Brain Cancer Clinical Trial Henry Ford Cancer Institute is first-in-the-world to enroll a glioblastoma patient in the GBM AGILE Trial (Adaptive… read more News | Proton Therapy | August 08, 2019 MD Anderson to Expand Proton Therapy Center The University of Texas MD Anderson Cancer Center unveiled plans to expand its Proton Therapy Center during a… read more
IHG Future Leaders intake for 2016It’s a corporate Australia-wide issue that representation of females in leadership is far exceeded by their male counterparts.Whilst the hospitality industry is not immune from the challenge, IHG (InterContinental Hotels Group) is investing in company culture to build a more sustainable model for gender diversity into the future.IHG COO Australasia & Japan, Karin Sheppard – the most senior authority in the region and a product of IHG’s global opportunities having held senior roles in the Middle East, Asia and Europe – acknowledges the gender gap in management level, particularly hotel general managers.Karin Sheppard, IHG COO Australasia & Japan“This is an industry-wide challenge; to create a more diverse workplace and encourage more females into general manager roles,” Ms Sheppard said.“It can be difficult to balance commercial realities with contemporary life – women often take time out from their career for family responsibilities, but it is the responsibility of employers to adapt and create an environment and culture that acknowledges these considerations.”IHG have implemented the most generous paid parental leave in the hospitality industry in Australia offering six weeks paid leave after two years employment which is increases to 12 weeks as tenure grows – valid across 80% of its hotels and at corporate office level. As a result around 95% of women return to IHG after parental leave.“There is an even gender representation on the AMEA Regional Operating Committee which Australia and New Zealand forms part of, with similar levels in my local leadership teams,” Ms Sheppard said.“This year we had a very encouraging 70% intake of women in our Future Leaders program which identifies high potential talent – all of which have expressed a desire to become General Managers in the future.”The 2015 Workplace Gender Equality report indicated that IHG’s gender pay gap is lower than both organisations of the same size and the accommodation/food service sector overall.Despite the progress Ms Sheppard believes there is more to be done.“As we mark International Women’s Day it is important to celebrate some of the significant progress made to date. Our aspiration is to create a culture that embraces diversity at all levels of the organisation and we remain committed to achieving this,” she said.IHG are set to open over ten hotels over the next three years in Australasia and in a competitive environment for sourcing talent, the company is focused on investment in its employees.“A strong diversity agenda is critical to the continued success of our business, as we seek to attract the strongest pool of talent to sustain the growth expected in this region,” she said. InterContinental Hotels GroupSource = InterContinental Hotels Group
Related16 ridiculously cheap places to go on holiday in 2017Want to save pounds on your holiday this year? We’ve put together 16 of the best places for budget travel in 2017, based on flight prices, accommodation, eating out and – most importantly – the average price of a beer. Here’s where’s cheap to travel this year, whether you’re up…Summer travel trends: winners and losers of British tourist trafficSkyscanner reveals this summer’s fastest growing destinations for British holidaymakersSkiing on the cheap: real value resortsSerbian skiing costs less than a third of some French resorts; Skyscanner reveals three secrets to cheap ski holidays. Turkey’s appeal as a potential holiday destination has increased thanks to an improvement in the quality of accommodation available in the country, it has been claimed.Nigel Harris, chief executive at Artemis Travel, believes Britons are looking for a combination of good accommodation, flexibility on cheap flights to Turkey and value for money when it comes to booking their summer vacation this year.He suggests that Turkey scores favourably in all three categories, and where once its downfall would have been the standard of accommodation, there has been a “definite” improvement in this area.”In the past, it was seen as a last minute choice, with poor quality accommodation,” he commented.”That has changed now and there is a definite move towards having very good accommodation out there; hotels and self catering [accommodation] have very good facilities.”Research conducted by M&S Money conforms with the view that more Brits are booking cheap flights to Turkey this year.The financial services provider’s figures show sales of the Turkish lira have increased by 46 percent in the first quarter of 2009 compared with the equivalent period in 2008. ReturnOne wayMulti-cityFromAdd nearby airports ToAdd nearby airportsDepart14/08/2019Return21/08/2019Cabin Class & Travellers1 adult, EconomyDirect flights onlySearch flights Map